The Louis K. Meisel Gallery is primarily interested in Fine Art that demonstrates knowledge of materials, craftsmanship, discipline, and a high level of quality. In the early 1970s, the Louis K. Meisel Gallery founded the Photorealism movement, which is the gallery's primary focus. The gallery remains the intellectual and economic support for this movement and its artists. Most recently, the gallery's focus has grown to include the genre of Realism, including the American pin-up artists of the 1930s through 1960s. The gallery has available hundreds of the finest original art works by the top pin-up artists from this period.
Louis K. Meisel has written comprehensive reference books on the gallery's disciplines, including The Great American Pin-Up, in 1996, Photorealism, in 1980, Photorealism Since 1980, in 1993, Photorealism at the Millenium (2002), and Photorealism in the Digital Age in 2013.